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Presenting a rare opportunity to acquire Villa Serena Inn, an iconic, historic Mediterranean-style landmark originally established in 1926 in the heart of Sarasota, Florida. Steeped in architectural character and artistic flair, this distinctive property features signature vibrant murals, lush courtyards, and versatile indoor-outdoor spaces. Perfectly positioned for a boutique hospitality operator, creative retreat center, or unique event venue, Villa Serena Inn combines old-world Florida charm with flexible commercial income potential. Key Property Highlights • Historic 1926 Architecture: Timeless design elements, classic masonry, and rich historical significance that appeal to cultural travelers and boutique seekers. • Turnkey Versatility: Currently configured to accommodate guest rentals, private workshops, community events, and artistic gatherings. • Prime Sarasota Location: Situated in one of Florida's most culturally vibrant and high-demand coastal markets, known for its arts scene, beaches, and thriving tourism. • Distinctive Aesthetic Appeal: Characterized by vibrant hand-painted murals, charming courtyards, and an intimate, secluded ambiance that creates an immediate sense of place. • Income-Producing Flexibility: Excellent potential for short-term luxury rentals, boutique bed-and-breakfast operations, micro-weddings, wellness retreats, or creative corporate events. Potential Uses • Boutique Inn / Bed & Breakfast/ Non transient apt. • Private Event & Wedding Venue • Creative Arts, Workshop, or Wellness Retreat Center • Corporate Executive Retreat Facility

Property Details

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Listed by Chris Poff of FLORIDA REAL ESTATE WIZARDS INC (407-908-8023)

Listings courtesy of StellarMLS as distributed by MLS GRID. Based on information submitted to the MLS GRID as of October 25, 2026 3:32 PM EDT. All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information. IDX information is provided exclusively for consumers’ personal noncommercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The data is deemed reliable but is not guaranteed by MLS GRID. The use of the MLS GRID Data may be subject to an end user license agreement.

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